White Powder GS-441524 CAS 1191237-69-0
- yanxi
- china
- 3-10days
- 100000kg/year
Introduction:
GS-441 is a competitive inhibitor of nucleoside triphosphate. It can inhibit the replication of several different types of RNA, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome, Ebola, Lassa fever, Junin and respiratory syncytium, etc., and has low cytotoxicity in a wide range of cell lines.
Function:
Gs-441 is phosphorylated to nucleoside monophosphate (NMP) by cell kinase, and then transformed into an active triphosphate metabolite (NTP structural analogue). In RNA synthesis, active NTP structure analogues act as natural nucleoside triphosphate competitors and compete with natural nucleosides (ATP, TTP, CTP, GTP) to participate in RNA transcription. When gs-441 is inserted into the transcripts, transcription will be terminated early, thus inhibiting the RNA transcription process.
White Powder GS-441524 CAS 1191237-69-0
Product Description
Name:(2R,3R,4S,5R)-2-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS No.:1191237-69-0
Place of Origin: China (Mainland)
Grade Standard: Pharmaceutical Grade
Brand Name: JINLAN PHARM
We recommend T/T or Escrow , D/P,D/A, Western Union or PayPal are also acceptable!
Delivery:
Express way as the following is:
(Shipping : TNT, Fedex, DHL,USP,EMS and so on)
Packaging:
Drum & plastic bags, Aluminum foiled bag, Zip lock bags
Our Company:
Our company advantage:
1.Small order is acceptable
2.Can provide sample for you
3.Have self-export rights
Our Advantages
Service:
1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.
Advantages:
1. Faster delivery: Sample order in stock and 3-7 days for bulk production.
2. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
3. After-Sale Service:
1)International Authorized Third-Party Test For The Products You Demand.
2)60 Days Warranty of quality of goods.
FAQ
Q1. How does your factory control quality?
A:All the raw material purchasing and production quality control are strictly following the ISO9001: 2008 management system. Besides, the full-featured detection equipment and GMP quality management system to provide the strongest guarantee for high quality product. We can provide our customers the detailed test report for the quality evaluation before the sample.
Q2. What's your main markets?
A:North America, Europe, Asia, etc.
Q3. What is your delivery term and delivery period?
A:We accept FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you. The sample within 3 days, and bulk order within 5 days.
Q4. What is your package?
A:Powder: PE bag, glass bottle or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
Liquid: glass bottle or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
Bulk order: Fiber drum or steel drum.
Q5. What is the payment term?
A:Normally we advise customers use Trade Assurance(is a free payment protection service for buyers is offered by Alibaba group), and we also receive T/T, Western Union or L/C.
Q6. Will you supply samples for test the quality?
A:We'd like to offer our customers the free samples for the quality evaluation for most products, but the shipping cost is borne by customers.
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